Erratum: Genetic modulation of training and transfer in older adults: BDNF Val66Met polymorphism is associated with wider useful field of view
نویسنده
چکیده
Western society has an increasing proportion of older adults. Increasing age is associated with a general decrease in the control over task-relevant mental processes. In the present study we investigated the possibility that successful transfer of game-based cognitive improvements to untrained tasks in elderly people is modulated by preexisting neuro-developmental factors as genetic variability related to levels of the brain-derived neurotrophic factor (BDNF), an important neuromodulator underlying cognitive processes. We trained participants, genotyped for the BDNF Val(66)Met polymorphism, on cognitive tasks developed to improve dynamic attention. Pre-training (baseline) and post-training measures of attentional processes (divided and selective attention) were acquired by means of the useful field of view task. As expected, Val/Val homozygous individuals showed larger beneficial transfer effects than Met/-carriers. Our findings support the idea that genetic predisposition modulates transfer effects.
منابع مشابه
The brain-derived neurotrophic factor (BDNF) gene Val66Met polymorphism affects memory performance in older adults.
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عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2011